Mutations of the Drosophila dDP, dE2F, and cyclin E Genes Reveal Distinct Roles for the E2F-DP Transcription Factor and Cyclin E during the G(1)-S Transition

Activation of heterodimeric E2F-DP transcription factors can drive the G(1)-S transition. Mutation of the Drosophila melanogaster dE2F gene eliminates transcriptional activation of several replication factors at the G(1)-S transition and compromises DNA replication. Here we describe a mutation in th...

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Autores principales: Duronio, Robert J., Bonnette, Peter C., O’Farrell, Patrick H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 1998
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC121467/
https://ncbi.nlm.nih.gov/pubmed/9418862
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