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Mutations of the Drosophila dDP, dE2F, and cyclin E Genes Reveal Distinct Roles for the E2F-DP Transcription Factor and Cyclin E during the G(1)-S Transition

Activation of heterodimeric E2F-DP transcription factors can drive the G(1)-S transition. Mutation of the Drosophila melanogaster dE2F gene eliminates transcriptional activation of several replication factors at the G(1)-S transition and compromises DNA replication. Here we describe a mutation in th...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Duronio, Robert J., Bonnette, Peter C., O’Farrell, Patrick H.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1998
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121467/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418862/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.141
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