Mutations of the Drosophila dDP, dE2F, and cyclin E Genes Reveal Distinct Roles for the E2F-DP Transcription Factor and Cyclin E during the G(1)-S Transition

Activation of heterodimeric E2F-DP transcription factors can drive the G(1)-S transition. Mutation of the Drosophila melanogaster dE2F gene eliminates transcriptional activation of several replication factors at the G(1)-S transition and compromises DNA replication. Here we describe a mutation in th...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Duronio, Robert J., Bonnette, Peter C., O’Farrell, Patrick H.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 1998
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC121467/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9418862/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.1.141
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