Mutations in Drosophila DP and E2F distinguish G(1)–S progression from an associated transcriptional program
The E2F transcription factor, a heterodimer of E2F and DP subunits, is capable of driving the G(1)–S transition of the cell cycle. However, mice in which the E2F-1 gene had been disrupted developed tumors, suggesting a negative role for E2F in controlling cell proliferation in some tissues. The cons...
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| Publicado no: | Genes Dev |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316409/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9271122/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.15.1999 |
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