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Multiple factors insulate Msh2-Msh6 mismatch repair activity from defects in Msh2 Domain I
DNA mismatch repair (MMR) is a highly conserved mutation avoidance mechanism that corrects DNA polymerase misincorporation errors. In initial steps in MMR, Msh2-Msh6 binds mispairs and small insertion/deletion loops and Msh2-Msh3 binds larger insertion/deletion loops. The msh2Δ1 mutation, which dele...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3163898/ https://ncbi.nlm.nih.gov/pubmed/21726567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.06.030 |
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