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Saccharomyces cerevisiae MSH2-MSH3 and MSH2-MSH6 complexes display distinct requirements for DNA binding Domain I in mismatch recognition.

In eukaryotic mismatch repair (MMR) MSH2-MSH6 initiates the repair of base-base and small insertion/deletion mismatches while MSH2-MSH3 repairs larger insertion/deletion mismatches. In this study we showed that the msh2Δ1 mutation, containing a complete deletion of the conserved mismatch recognition...

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Detalhes bibliográficos
Main Authors: Lee, Susan D., Surtees, Jennifer A., Alani, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1805781/
https://ncbi.nlm.nih.gov/pubmed/17157869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.10.09
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