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Distinct requirements within the Msh3 nucleotide binding pocket for mismatch and double-strand break repair

In Saccharomyces cerevisiae, repair of insertion/deletion loops is carried out by Msh2-Msh3-mediated mismatch repair (MMR). Msh2-Msh3 is also required for 3’ non-homologous tail removal (3’NHTR) in double-strand break repair. In both pathways, Msh2-Msh3 binds double-strand/single-strand junctions an...

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Detalhes bibliográficos
Main Authors: Kumar, Charanya, Williams, Gregory M., Havens, Brett, Dinicola, Michelle, Surtees, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657845/
https://ncbi.nlm.nih.gov/pubmed/23458407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.02.024
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