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DNA Mismatch Repair-Induced Double-Strand Breaks

Escherichia coli dam mutants are sensitized to the cytotoxic action of base analogs, cisplatin and N-methyl-N’-nitro-N-nitrosoguanidine (MNNG), while their mismatch repair (MMR)-deficient derivatives are tolerant to these agents. We showed previously, using pulse field gel electrophoresis, that MMR-...

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Bibliografiske detaljer
Main Authors: Nowosielska, Anetta, Marinus, M. G.
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175267/
https://ncbi.nlm.nih.gov/pubmed/17827074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.07.015
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