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DNA Mismatch Repair-Induced Double-Strand Breaks
Escherichia coli dam mutants are sensitized to the cytotoxic action of base analogs, cisplatin and N-methyl-N’-nitro-N-nitrosoguanidine (MNNG), while their mismatch repair (MMR)-deficient derivatives are tolerant to these agents. We showed previously, using pulse field gel electrophoresis, that MMR-...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2175267/ https://ncbi.nlm.nih.gov/pubmed/17827074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2007.07.015 |
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