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A Role for DNA Mismatch Repair Protein Msh2 in Error-Prone Double-Strand-Break Repair in Mammalian Chromosomes

We examined error-prone nonhomologous end joining (NHEJ) in Msh2-deficient and wild-type Chinese hamster ovary cell lines. A DNA substrate containing a thymidine kinase (tk) gene fused to a neomycin-resistance (neo) gene was stably integrated into cells. The fusion gene was rendered nonfunctional du...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Smith, Jason A., Waldman, Barbara Criscuolo, Waldman, Alan S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Genetics Society of America 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449728/
https://ncbi.nlm.nih.gov/pubmed/15781695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.039362
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