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Kinetic Discrimination in Recognition of DNA Quadruplex Targets by Guanine-Rich Heteroquadruplex-Forming PNA Probes
Guanine-rich peptide nucleic acid probes hybridize to DNA G quadruplex targets with high affinity, forming PNA-DNA heteroquadruplexes. We report a surprising degree of kinetic discrimination for PNA heteroquadruplex formation with a series of DNA targets. The fastest hybridization is observed for ta...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3163151/ https://ncbi.nlm.nih.gov/pubmed/21717030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cc12805a |
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