The Effect of ACACB cis-Variants on Gene Expression and Metabolic Traits

BACKGROUND: Acetyl Coenzyme A carboxylase β (ACACB) is the rate-limiting enzyme in fatty acid oxidation, and continuous fatty acid oxidation in Acacb knock-out mice increases insulin sensitivity. Systematic human studies have not been performed to evaluate whether ACACB variants regulate gene expres...

Full description

Saved in:
Bibliographic Details
Main Authors: Ma, Lijun, Mondal, Ashis K., Murea, Mariana, Sharma, Neeraj K., Tönjes, Anke, Langberg, Kurt A., Das, Swapan K., Franks, Paul W., Kovacs, Peter, Antinozzi, Peter A., Stumvoll, Michael, Parks, John S., Elbein, Steven C., Freedman, Barry I.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162605/
https://ncbi.nlm.nih.gov/pubmed/21887335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023860
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items