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Type 2 Diabetes (T2D) Associated Polymorphisms Regulate Expression of Adjacent Transcripts in Transformed Lymphocytes, Adipose, and Muscle from Caucasian and African-American Subjects

CONTEXT: Genome-wide association scans (GWAS) have identified novel single nucleotide polymorphisms (SNPs) that increase T2D susceptibility and indicated the role of nearby genes in T2D pathogenesis. OBJECTIVE: We hypothesized that T2D-associated SNPs act as cis-regulators of nearby genes in human t...

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Detalhes bibliográficos
Main Authors: Sharma, Neeraj K., Langberg, Kurt A., Mondal, Ashis K., Elbein, Steven C., Das, Swapan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048324/
https://ncbi.nlm.nih.gov/pubmed/21084393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-1754
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