Analysis of Osteocalcin as a Candidate Gene for Type 2 Diabetes (T2D) and Intermediate Traits in Caucasians and African Americans

Recent studies in mice and human identified osteocalcin (OCN) as a bone-derived hormone that modulates insulin secretion and insulin sensitivity. OCN is synthesized by the bone gamma-carboxyglutamate protein (BGLAP) gene located in the well replicated region of type 2 diabetes (T2D) linkage on chrom...

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Main Authors: Das, Swapan K., Sharma, Neeraj K., Elbein, Steven C.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3304587/
https://ncbi.nlm.nih.gov/pubmed/20592451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/DMA-2010-0701
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