The Effect of ACACB cis-Variants on Gene Expression and Metabolic Traits

BACKGROUND: Acetyl Coenzyme A carboxylase β (ACACB) is the rate-limiting enzyme in fatty acid oxidation, and continuous fatty acid oxidation in Acacb knock-out mice increases insulin sensitivity. Systematic human studies have not been performed to evaluate whether ACACB variants regulate gene expres...

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Auteurs principaux: Ma, Lijun, Mondal, Ashis K., Murea, Mariana, Sharma, Neeraj K., Tönjes, Anke, Langberg, Kurt A., Das, Swapan K., Franks, Paul W., Kovacs, Peter, Antinozzi, Peter A., Stumvoll, Michael, Parks, John S., Elbein, Steven C., Freedman, Barry I.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162605/
https://ncbi.nlm.nih.gov/pubmed/21887335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023860
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