Interaction of RNA Polymerase II Fork Loop 2 with Downstream Non-template DNA Regulates Transcription Elongation

Fork loop 2 is a small semiconservative segment of the larger fork domain in the second largest Rpb2 subunit of RNA polymerase II (Pol II). This flexible loop, juxtaposed at the leading edge of transcription bubble, has been proposed to participate in DNA strand separation, translocation along DNA,...

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Bibliographic Details
Main Authors: Kireeva, Maria L., Domecq, Céline, Coulombe, Benoit, Burton, Zachary F., Kashlev, Mikhail
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Enzymology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162450/
https://ncbi.nlm.nih.gov/pubmed/21730074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.260844
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