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mSIN1 Protein Mediates SGK1 Protein Interaction with mTORC2 Protein Complex and Is Required for Selective Activation of the Epithelial Sodium Channel

The mammalian target of rapamycin (mTOR) plays a central role in the regulation of a number of cellular processes including growth, metabolism, and ion transport. mTOR is found in two multiprotein complexes, mTORC1 and mTORC2, which phosphorylate distinct substrates and regulate distinct cellular pr...

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Bibliographic Details
Main Authors: Lu, Ming, Wang, Jian, Ives, Harlan E., Pearce, David
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162425/
https://ncbi.nlm.nih.gov/pubmed/21757730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.257592
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