Carregant...
The resveratrol analogue, 2,3′,4,5′-tetramethoxystilbene, does not inhibit CYP gene expression, enzyme activity and benzo[a]pyrene–DNA adduct formation in MCF-7 cells exposed to benzo[a]pyrene
Exposure to carcinogenic polycyclic aromatic hydrocarbons (PAHs) induces cytochrome P450 (CYP) 1A1 and 1B1 enzymes, which biotransform PAHs resulting in the formation of DNA adducts. We hypothesised that 2,3′,4,5′-tetramethoxystilbene (TMS), an analogue of resveratrol and a potent CYP1B1 inhibitor,...
Guardat en:
| Autors principals: | , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2011
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3162036/ https://ncbi.nlm.nih.gov/pubmed/21669939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/ger024 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|