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Heparanase affects secretory granule homeostasis of mouse mast cells through degrading heparin
BACKGROUND: Heparanase degradation of heparan sulfate plays important roles in a number of pathological processes, including inflammation. In vitro experiments show that heparanase is capable of degrading heparin, a polysaccharide present in mast cells where it has a key role in promoting the storag...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3160500/ https://ncbi.nlm.nih.gov/pubmed/21575986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.04.011 |
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