Newly Generated Heparanase Knock-Out Mice Unravel Co-Regulation of Heparanase and Matrix Metalloproteinases

BACKGROUND: Heparanase, a mammalian endo-β-D-glucuronidase, specifically degrades heparan sulfate proteoglycans ubiquitously associated with the cell surface and extracellular matrix. This single gene encoded enzyme is over-expressed in most human cancers, promoting tumor metastasis and angiogenesis...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zcharia, Eyal, Jia, Juan, Zhang, Xiao, Baraz, Lea, Lindahl, Ulf, Peretz, Tamar, Vlodavsky, Israel, Li, Jin-Ping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2009
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664924/
https://ncbi.nlm.nih.gov/pubmed/19360105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005181
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia