Implications of Heparanase on Heparin Synthesis and Metabolism in Mast Cells

Heparin is a polysaccharide expressed in animal connective tissue-type mast cells. Owing to the special pentasaccharide sequence, heparin specifically binds to antithrombin (AT) and increases the inhibitory activity of AT towards coagulation enzymes. Heparin isolated from porcine intestinal mucosa h...

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Detalhes bibliográficos
Main Authors: Marco Maccarana, Juan Jia, Honglian Li, Xiao Zhang, Israel Vlodavsky, Jin-Ping Li
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-04-01
Colecção:International Journal of Molecular Sciences
Assuntos:
antithrombin
heparanase
heparin
mast cells
Acesso em linha:https://www.mdpi.com/1422-0067/23/9/4821
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