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A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers
Major histocompatibility complex class I (MHCI) and MHCII proteins differ in structure and sequence. To understand how T cell receptors (TCRs) can use the same set of variable regions to bind both proteins, we have presented the first comparison of a single TCR bound to both MHCI and MHCII ligands....
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3160269/ https://ncbi.nlm.nih.gov/pubmed/21683626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.04.017 |
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