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Mycobacterium tuberculosis triggers host type I interferon signaling to regulate IL-1β production in human macrophages
Mycobacterium tuberculosis is a virulent intracellular pathogen that survives in macrophages even in the presence of an intact adaptive immune response. Type I interferons (IFN) have been shown to exacerbate tuberculosis in mice and to be associated with disease progression in infected humans. Never...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159798/ https://ncbi.nlm.nih.gov/pubmed/21784976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100926 |
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