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Anti-TNF-Alpha Therapy Enhances the Effects of Enzyme Replacement Therapy in Rats with Mucopolysaccharidosis Type VI

BACKGROUND: Although enzyme replacement therapy (ERT) is available for several lysosomal storage disorders, the benefit of this treatment to the skeletal system is very limited. Our previous work has shown the importance of the Toll-like receptor 4/TNF-alpha inflammatory pathway in the skeletal path...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Eliyahu, Efrat, Wolfson, Theodore, Ge, Yi, Jepsen, Karl J., Schuchman, Edward H., Simonaro, Calogera M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159569/
https://ncbi.nlm.nih.gov/pubmed/21887218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022447
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