HGF and c-Met Participate in Paracrine Tumorigenic Pathways in Head and Neck Squamous Cell Cancer

PURPOSE: We determined hepatocyte growth factor (HGF) and c-Met expression and signaling in human head and neck squamous cell carcinoma (HNSCC) cells and primary tissues and tested the ability of c-Met tyrosine kinase inhibitors (TKI) to block HGF-induced biological signaling. EXPERIMENTAL DESIGN: E...

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Main Authors: Knowles, Lynn M., Stabile, Laura P., Egloff, Ann Marie, Rothstein, Mary E., Thomas, Sufi M., Gubish, Christopher T., Lerner, Edwina C., Seethala, Raja R., Suzuki, Shinsuke, Quesnelle, Kelly M., Morgan, Sarah, Ferris, Robert L., Grandis, Jennifer R., Siegfried, Jill M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159511/
https://ncbi.nlm.nih.gov/pubmed/19470725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-3252
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