HGF and c-Met Participate in Paracrine Tumorigenic Pathways in Head and Neck Squamous Cell Cancer

PURPOSE: We determined hepatocyte growth factor (HGF) and c-Met expression and signaling in human head and neck squamous cell carcinoma (HNSCC) cells and primary tissues and tested the ability of c-Met tyrosine kinase inhibitors (TKI) to block HGF-induced biological signaling. EXPERIMENTAL DESIGN: E...

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Bibliografiska uppgifter
Huvudupphovsmän: Knowles, Lynn M., Stabile, Laura P., Egloff, Ann Marie, Rothstein, Mary E., Thomas, Sufi M., Gubish, Christopher T., Lerner, Edwina C., Seethala, Raja R., Suzuki, Shinsuke, Quesnelle, Kelly M., Morgan, Sarah, Ferris, Robert L., Grandis, Jennifer R., Siegfried, Jill M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159511/
https://ncbi.nlm.nih.gov/pubmed/19470725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-3252
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