Computational identification of insertional mutagenesis targets for cancer gene discovery

Insertional mutagenesis is a potent forward genetic screening technique used to identify candidate cancer genes in mouse model systems. An important, yet unresolved issue in the analysis of these screens, is the identification of the genes affected by the insertions. To address this, we developed Ke...

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Autores principales: de Jong, Johann, de Ridder, Jeroen, van der Weyden, Louise, Sun, Ning, van Uitert, Miranda, Berns, Anton, van Lohuizen, Maarten, Jonkers, Jos, Adams, David J., Wessels, Lodewyk F. A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2011
Materias:
Methods Online
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159484/
https://ncbi.nlm.nih.gov/pubmed/21652642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr447
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