Computational identification of insertional mutagenesis targets for cancer gene discovery

Insertional mutagenesis is a potent forward genetic screening technique used to identify candidate cancer genes in mouse model systems. An important, yet unresolved issue in the analysis of these screens, is the identification of the genes affected by the insertions. To address this, we developed Ke...

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Bibliografiske detaljer
Main Authors: de Jong, Johann, de Ridder, Jeroen, van der Weyden, Louise, Sun, Ning, van Uitert, Miranda, Berns, Anton, van Lohuizen, Maarten, Jonkers, Jos, Adams, David J., Wessels, Lodewyk F. A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2011
Fag:
Methods Online
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159484/
https://ncbi.nlm.nih.gov/pubmed/21652642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr447
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