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Dimer formation and conformational flexibility ensure cytoplasmic stability and nuclear accumulation of Elk-1
The ETS (E26) protein Elk-1 serves as a paradigm for mitogen-responsive transcription factors. It is multiply phosphorylated by mitogen-activated protein kinases (MAPKs), which it recruits into pre-initiation complexes on target gene promoters. However, events preparatory to Elk-1 phosphorylation ar...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159454/ https://ncbi.nlm.nih.gov/pubmed/21543455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr266 |
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