Nalaganje...

Restoration of G1 chemo/radioresistance and double-strand-break repair proficiency by wild-type but not endonuclease-deficient Artemis

Deficiency in Artemis is associated with lack of V(D)J recombination, sensitivity to radiation and radiomimetic drugs, and failure to repair a subset of DNA double-strand breaks (DSBs). Artemis harbors an endonuclease activity that trims both 5′- and 3′-ends of DSBs. To examine whether endonucleolyt...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Mohapatra, Susovan, Kawahara, Misako, Khan, Imran S., Yannone, Steven M., Povirk, Lawrence F.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159448/
https://ncbi.nlm.nih.gov/pubmed/21531702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr257
Oznake: Označite
Brez oznak, prvi označite!