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An RNA aptamer perturbs heat shock transcription factor activity in Drosophila melanogaster
Heat shock transcription factor (HSF1) is a conserved master regulator that orchestrates the protection of normal cells from stress. However, HSF1 also protects abnormal cells and is required for carcinogenesis. Here, we generate an highly specific RNA aptamer (iaRNA(HSF1)) that binds Drosophila HSF...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3159435/ https://ncbi.nlm.nih.gov/pubmed/21576228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr206 |
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