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TFIIB aptamers inhibit transcription by perturbing PIC formation at distinct stages

Transcription in eukaryotes is a multistep process involving the assembly and disassembly of numerous inter- and intramolecular interactions between transcription factors and nucleic acids. The roles of each of these interactions and the regions responsible for them have been identified and studied...

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Detalhes bibliográficos
Main Authors: Sevilimedu, Aarti, Shi, Hua, Lis, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396426/
https://ncbi.nlm.nih.gov/pubmed/18403417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn163
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