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RNA aptamers directed to discrete functional sites on a single protein structural domain

Cellular regulatory networks are organized such that many proteins have few interactions, whereas a few proteins have many. These densely connected protein “hubs” are critical for the system-wide behavior of cells, and the capability of selectively perturbing a subset of interactions at these hubs i...

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Detalhes bibliográficos
Main Authors: Shi, Hua, Fan, Xiaochun, Sevilimedu, Aarti, Lis, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820654/
https://ncbi.nlm.nih.gov/pubmed/17360423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607805104
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