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RNA aptamers as effective protein antagonists in a multicellular organism

RNA aptamers selected against proteins can be used to modulate specific protein function. Expression of such reagents in cells and whole organisms could provide a means of dissecting and controlling molecular mechanisms in vivo. We demonstrate that Drosophila B52 protein can be specifically inhibite...

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Detalhes bibliográficos
Main Authors: Shi, Hua, Hoffman, Bryan E., Lis, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17837/
https://ncbi.nlm.nih.gov/pubmed/10468557
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