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Structure of the HIV-1 frameshift site RNA bound to a small molecule inhibitor of viral replication

Programmed -1 translational frameshifting is an essential event in the replication cycle of HIV. Frameshifting is required for expression of the viral Pol proteins, and drug-like molecules that target this process may inhibit HIV replication. A small molecule stimulator of HIV-1 frameshifting and in...

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Detaylı Bibliyografya
Asıl Yazarlar: Marcheschi, Ryan J., Tonelli, Marco, Kumar, Arvind, Butcher, Samuel E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158809/
https://ncbi.nlm.nih.gov/pubmed/21648432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200082d
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