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Structure of the HIV-1 frameshift site RNA bound to a small molecule inhibitor of viral replication
Programmed -1 translational frameshifting is an essential event in the replication cycle of HIV. Frameshifting is required for expression of the viral Pol proteins, and drug-like molecules that target this process may inhibit HIV replication. A small molecule stimulator of HIV-1 frameshifting and in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3158809/ https://ncbi.nlm.nih.gov/pubmed/21648432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200082d |
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