Down-Regulated NOD2 by Immunosuppressants in Peripheral Blood Cells in Patients with SLE Reduces the Muramyl Dipeptide-Induced IL-10 Production

BACKGROUND: Pattern recognition receptors (PRRs) such as Toll-like receptors are aberrantly expressed of peripheral blood mononuclear cells (PBMCs) in systemic lupus erythematosus (SLE) patients, for playing immunopathological roles. METHODOLOGY/PRINCIPAL FINDINGS: We investigated the expression and...

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Autores principales: Yu, Shui-Lian, Wong, Chun-Kwok, Wong, Purple Tsz-Yan, Chen, Da-Peng, Szeto, Cheuk-Chun, Li, Edmund K., Tam, Lai-Shan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158772/
https://ncbi.nlm.nih.gov/pubmed/21886831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023855
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