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Foxp3(+) regulatory T cells exert asymmetric control over murine helper responses by inducing Th2 cell apoptosis

Foxp3(+) regulatory T cells play a pivotal role in maintaining self-tolerance and immune homeostasis. In the absence of regulatory T cells, generalized immune activation and multiorgan T cell–driven pathology occurs. Although the phenomenon of immunologic control by Foxp3(+) regulatory T cells is we...

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Autores principales: Tian, Lei, Altin, John A., Makaroff, Lydia E., Franckaert, Dean, Cook, Matthew C., Goodnow, Christopher C., Dooley, James, Liston, Adrian
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158716/
https://ncbi.nlm.nih.gov/pubmed/21715314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-04-346056
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