Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function

Multiple independent mutations in neuroligin genes were identified in patients with familial autism, including the R451C substitution in neuroligin-3 (NL3). Previous studies showed that NL3(R451C) knock-in mice exhibited modestly impaired social behaviors, enhanced water maze learning abilities, and...

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Detaylı Bibliyografya
Asıl Yazarlar: Etherton, Mark, Földy, Csaba, Sharma, Manu, Tabuchi, Katsuhiko, Liu, Xinran, Shamloo, Mehrdad, Malenka, Robert C., Südhof, Thomas C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158170/
https://ncbi.nlm.nih.gov/pubmed/21808020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111093108
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