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Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function
Multiple independent mutations in neuroligin genes were identified in patients with familial autism, including the R451C substitution in neuroligin-3 (NL3). Previous studies showed that NL3(R451C) knock-in mice exhibited modestly impaired social behaviors, enhanced water maze learning abilities, and...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3158170/ https://ncbi.nlm.nih.gov/pubmed/21808020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111093108 |
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