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Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer
In the majority of cases, advanced prostate cancer responds initially to androgen deprivation therapy by depletion of gonadal testosterone. The response is usually transient, and metastatic tumors almost invariably eventually progress as castration-resistant prostate cancer (CRPC). The development o...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3158152/ https://ncbi.nlm.nih.gov/pubmed/21795608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107898108 |
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