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Dihydrotestosterone synthesis from adrenal precursors does not involve testosterone in castration-resistant prostate cancer

Androgen deprivation therapy is the frontline treatment for metastatic prostate cancer; however, because the majority of cases of advanced prostate cancer progress to castration-resistant prostate cancer (CRPC), there is a considerable need to better understand the synthesis of intratumoral concentr...

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Détails bibliographiques
Auteurs principaux: Campbell, Tessa J, Tindall, Donald J, Figg, William D
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367713/
https://ncbi.nlm.nih.gov/pubmed/22336886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.13.5.19608
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