Prolonged Infusion of Angiotensin II in apoE(−/−) Mice Promotes Macrophage Recruitment with Continued Expansion of Abdominal Aortic Aneurysm

Angiotensin II (AngII) infusion initiates abdominal aortic aneurysm (AAA) development due to medial disruption and results in luminal dilation and thrombus formation. The objective of this study was to determine whether AAA progressed during protracted AngII infusion. Male apoE(−/−) mice were infuse...

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Detalhes bibliográficos
Main Authors: Rateri, Debra L., Howatt, Deborah A., Moorleghen, Jessica J., Charnigo, Richard, Cassis, Lisa A., Daugherty, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157213/
https://ncbi.nlm.nih.gov/pubmed/21763672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.049
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