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Angiotensin II infusion promotes ascending aortic aneurysms: attenuation by CCR2 deficiency in apoE(−/−) mice

AngII (angiotensin II) induces atherosclerosis and AAAs (abdominal aortic aneurysms) through multiple proposed mechanisms, including chemotaxis. Therefore, we determined the effects of whole-body deficiency of the chemokine receptor CCR2 (CC chemokine receptor 2) on these diseases. To meet this obje...

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Detalhes bibliográficos
Main Authors: Daugherty, Alan, Rateri, Debra L., Charo, Israel F., Owens, A. Phillip, Howatt, Deborah A., Cassis, Lisa A.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841499/
https://ncbi.nlm.nih.gov/pubmed/20088827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20090372
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