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PD123319 Augments Angiotensin II-Induced Abdominal Aortic Aneurysms through an AT2 Receptor-Independent Mechanism

BACKGROUND: AT2 receptors have an unclear function on development of abdominal aortic aneurysms (AAAs), although a pharmacological approach using the AT2 receptor antagonist PD123319 has implicated a role. The purpose of the present study was to determine the role of AT2 receptors in AngII-induced A...

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Détails bibliographiques
Auteurs principaux: Daugherty, Alan, Rateri, Debra L., Howatt, Deborah A., Charnigo, Richard, Cassis, Lisa A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625148/
https://ncbi.nlm.nih.gov/pubmed/23593499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061849
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