Interleukin-17A Promotes Early but Attenuates Established Disease in Crescentic Glomerulonephritis in Mice

T helper (Th)17 cells might contribute to immune-mediated renal injury. Thus, we sought to define the time course of IL-17A-induced kidney damage and examined the relation between Th17 and Th1 cells in a model of crescentic anti-glomerular basement membrane glomerulonephritis. Renal injury and immun...

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Autors principals: Odobasic, Dragana, Gan, Poh-Yi, Summers, Shaun A., Semple, Tim J., Muljadi, Ruth C.M., Iwakura, Yoichiro, Kitching, A. Richard, Holdsworth, Stephen R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2011
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157183/
https://ncbi.nlm.nih.gov/pubmed/21741931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.05.039
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