Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice

In nonalcoholic fatty liver disease (NAFLD), depletion of hepatic antioxidants may contribute to the progression of steatosis to nonalcoholic steatohepatitis (NASH) by increasing oxidative stress that produces lipid peroxidation, inflammation, and fibrosis. We investigated whether depletion of gluta...

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Detalhes bibliográficos
Main Authors: Haque, Jamil A, McMahan, Ryan S, Campbell, Jean S, Shimizu-Albergine, Masami, Wilson, Angela M, Botta, Dianne, Bammler, Theo K, Beyer, Richard P, Montine, Thomas J, Yeh, Matthew M, Kavanagh, Terrance J, Fausto, Nelson
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156113/
https://ncbi.nlm.nih.gov/pubmed/20548286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.112
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