Glutathione (GSH) and the GSH synthesis gene Gclm modulate vascular reactivity in mice

Oxidative stress has been implicated in the development of vascular disease and in the promotion of endothelial dysfunction via the reduction in bioavailable nitric oxide (NO•). Glutathione (GSH) is a tripeptide thiol antioxidant that is utilized by glutathione peroxidase (GPx) to scavenge reactive...

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Hauptverfasser: Weldy, Chad S., Luttrell, Ian P., White, Collin C., Morgan-Stevenson, Vicki, Bammler, Theo K., Beyer, Richard P., Afsharinejad, Zahra, Kim, Francis, Chitaley, Kanchan, Kavanagh, Terrance J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625031/
https://ncbi.nlm.nih.gov/pubmed/22824862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.07.006
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