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Attenuated progression of diet-induced steatohepatitis in glutathione-deficient mice

In nonalcoholic fatty liver disease (NAFLD), depletion of hepatic antioxidants may contribute to the progression of steatosis to nonalcoholic steatohepatitis (NASH) by increasing oxidative stress that produces lipid peroxidation, inflammation, and fibrosis. We investigated whether depletion of gluta...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Haque, Jamil A, McMahan, Ryan S, Campbell, Jean S, Shimizu-Albergine, Masami, Wilson, Angela M, Botta, Dianne, Bammler, Theo K, Beyer, Richard P, Montine, Thomas J, Yeh, Matthew M, Kavanagh, Terrance J, Fausto, Nelson
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156113/
https://ncbi.nlm.nih.gov/pubmed/20548286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.112
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