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Toll-Like Receptor 4 and Myeloid Differentiation Factor 88 Provide Mechanistic Insights Into the Cause and Effects of Interleukin-6 Activation in Mouse Liver Regeneration

Partial hepatectomy (PH) consistently results in an early increase of circulating interleukin- 6 (IL-6), which is thought to play a major role in liver regeneration. Activation of this cytokine after PH requires the adaptor protein, MyD88, but the specific MyD88-related receptors involved remain uni...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Vaquero, Javier, Campbell, Jean S., Haque, Jamil, McMahan, Ryan S., Riehle, Kimberly J., Bauer, Renay L., Fausto, Nelson
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247827/
https://ncbi.nlm.nih.gov/pubmed/21574169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.24420
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