GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth

We report here the identification of GIDE, a mitochondrially located E3 ubiquitin ligase. GIDE contains a C-terminal Ring finger domain, which is mostly conserved with those of the IAP family members, and which is required for its E3 ligase activity. Overexpression of GIDE induces apoptosis via a pa...

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Détails bibliographiques
Auteurs principaux: Zhang, Bicheng, Huang, Jun, Li, Hong-Liang, Liu, Ting, Wang, Yan-Yi, Waterman, Paul, Mao, Ai-Ping, Xu, Liang-Guo, Zhai, Zhonghe, Liu, Depei, Marrack, Philippa, Shu, Hong-Bing
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156110/
https://ncbi.nlm.nih.gov/pubmed/18591963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2008.75
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